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Part-human part-mouse brain developed in science breakthrough (https://www.bbc.com)

55 points by marc__1 3 days ago | 34 comments | View on ycombinator

theseamusjames 3 days ago |

Great news: we're excellent at curing mice of diseases. All this time we've been trying to find drugs that have the same effect in humans as they do in mice, but until now no one has had the insight or bravery to ask the question, "What if we just made people more mouse?" Exciting stuff.

autoexec 3 days ago |

The article walks the headline back pretty quickly. Parts of human brains in mice becomes "pieces of brain-like tissue" made from skin cells and formed into "collections of connected, living cells" followed by a line on how there's "no indication that what's being created here are mice that can think like humans, or a human brain in a mouse body." and that the human cells started to look and function like the outer layer of the mouse's brain as opposed to looking or functioning like a part of a human brain.

It's still kind of neat though and I hope it's actually somehow useful for something.

bygosh 3 days ago |

> The scientists said their work, published in the journal Nature, was carried out with independent ethical scrutiny.

oh, I guess there's nothing to be concerned about.

zhaoziyuan2000 3 days ago |

Does this remind anyone of that novel Flowers for Algernon..?

d--b 3 days ago |

Sounds like “the scret of NIMH” an animated movie from the 80s, where intelligent mice escape a science lab.

https://en.wikipedia.org/wiki/The_Secret_of_NIMH

jdalsgaard 3 days ago |

Forget Artificial Intelligence, _Real Intelligence_ is coming...

(Background material: https://hitchhikers.fandom.com/wiki/Mice)

someothherguyy 3 days ago |

https://www.nature.com/articles/s41586-026-11032-2

Developmental xenocortication using human-derived organoids in mice

LoganDark 3 days ago |

I feel like it's going to be difficult to characterize how mental illness translates to mice, even if you get human cells in there. ("psychiatric diseases" = mental illness)

bsimpson 3 days ago |

They're Pinky and the Brain...yes: Pinky and the Brain...

yieldcrv 3 days ago |

> While mice with brains that are partly human might sound like a Kafkaesque experiment, the scientists said these are not "mice that think like humans".

oh, thank god

edoceo 3 days ago |

Hook that thing up to the Torment Nexus and see what the next tech-bubble will be!

seydor 3 days ago |

So now we have found a way to use brain organoids by grafting and growing them inside mouse heads. Those Frankenmice will be used as a platform from now on.

I m looking forward to talk to the first language-capable Frankenmouse.

igleria 3 days ago |

Dr Moreau would be proud

freebsd_lovefes 3 days ago |

Humans genetically-engineered with no cerebral cortex fitted with a whole bunch of computing technology inside the craniums - coming to a city near you soon.

Oh, wait, has that already happened, and you thought someone was going to tell you about it? They thought they couldn't fake all the head MRI scans to cover up for THAT?

Multiple variations of this reality may exist. I'd so read a thriller book about this...but none have been written, strangely enough.

yawpitch 3 days ago |

Narf!

0xDECAF 3 days ago |

ed...ward?

eluru 3 days ago |

i was expecting for cat-humans but this will do

echelon_musk 3 days ago |

Terrifying.

fnordpiglet 3 days ago |

I for one welcome our part human part mouse brain overlords.

redder23 3 days ago |

[dead]